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Science and the US Supreme Court: The cases to watch in 2. Nature News & Comment.

• Are you in a confusion which best golf GPS watch to choose? Here we are to help you out! With the HONEST and PROFESSIONAL reviews.
• Fox Searchlight released the official trailer for Guillermo del Toro's The Shape of Water today.
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Donald Hobern/Flickr/CC BYThe Utah prairie dog is at the centre of a legal battle over endangered- species protections. On 3. 1 January, US President Donald Trump nominated Neil Gorsuch to the Supreme Court. Gorsuch, a conservative federal appeals court judge, would fill the vacancy left by the death of conservative justice Antonin Scalia in February 2. Since then, the court has been split evenly between conservative and liberal justices; if Gorsuch is confirmed by the US Senate, the court's ideological centre would shift towards the conservative. Nature looks at the science- related cases that are already on the court's agenda this year, and others that are likely to advance to the highest court in the land. Biological drugs. The court will hear a pair of patent cases dealing with biological drugs.

Because these living products are impossible to copy exactly, companies seeking to make cheaper generic versions called biosimilars must prove that their manufacturing process is as safe and effective as that of the original product. Only then will the US Food and Drug Administration (FDA) allow a biosimilar onto the market.

The Supreme Court will decide whether such manufacturing processes themselves are trade secrets. In 2. 01. 4, Sandoz, the generics arm of Swiss pharmaceutical giant Novartis, patented a generic version of the biological cancer drug filgrastim. Amgen, the company in Thousand Oaks, California, that makes filgrastim, then sued Sandoz, alleging that it infringed Amgen’s patents and failed to comply with legal requirements to disclose its manufacturing process to Amgen.

Sandoz later countersued, challenging a federal requirement that a biosimilar maker wait six months after approval before marketing its therapy. Because the FDA has already evaluated each company’s manufacturing process for safety and efficacy, the court’s ruling will have no bearing on patient care, says Arti Rai, a legal expert at Duke University in Durham, North Carolina.

But the ruling could have a massive effect on the biologics market. Patents for natural products. The court may also revisit when patents can be awarded for products made by naturally occurring processes. In 2. 01. 2, the Supreme Court ruled that Prometheus Laboratories in San Diego, California, could not patent a kit that measured chemicals in a patient’s blood to determine whether a drug is working.

And in 2. 01. 3, it ruled that Myriad Genetics of Salt Lake City, Utah, could not patent a gene linked to breast cancer. The decisions shocked the biotechnology industry, because they implied that a wide array of products could not be patented, and companies are now hoping that the Supreme Court will provide clarity by taking another case. Although in 2. 01.

DNA in maternal blood samples, Rai says that most experts in the field expect that it will accept a similar case soon. Water- pollution limits. The court agreed in January to hear a case that will determine which lower court should be the first to hear a lawsuit brought by developers challenging federal water- pollution regulations. The case could also decide whether the Clean Water Act applies to small tributaries and watersheds that contain as much as 6.

United States. The law was originally intended to protect lakes and other navigable waterways from pollution, but the administration of former president Barack Obama expanded it to cover more waters.“It’s a big- time rule,” says Patrick Parenteau, an environmental lawyer at the Vermont Law School in South Royalton. Among them is a case filed by Oklahoma attorney general Scott Pruitt — Trump’s pick to lead the US Environmental Protection Agency (EPA), which enforces the Clean Water Act. Endangered species. Another case that could reach the court is a challenge to the Endangered Species Act that is now pending in Utah, Parenteau says. Property owners filed the suit to protest government restrictions on harassing or killing the endangered Utah prairie dog, even on private lands. In 2. 01. 4, a federal judge ruled that the Endangered Species Act cannot be used to protect the prairie dog. When the US Congress enacted the species law, it relied on a provision in the US Constitution that allows the government to regulate interstate commerce.

Because the prairie dog appears to exist only in Utah, the interstate commerce provision — and thus, the endangered species law — does not apply, the federal judge said. The US Fish and Wildlife Service, which administers the endangered- species law, has appealed against the ruling, but that court’s decision has been pending for a year. Parenteau says that the appeals' court's long deliberation time suggests that it may uphold the Utah judge's ruling. If the case ultimately reaches the Supreme Court, it could affect whether the federal government can protect other species that are only found in one state. Climate- change rules. The most closely watched environmental case that might appear before the court deals with the Clean Power Plan, Obama’s 2. Twenty- seven states have sued the EPA over the rule, saying that the agency’s authority to regulate air quality does not extend to greenhouse- gas emissions.

A federal court in Washington DC heard the case in September 2. Jonathan Adler, a legal expert at Case Western Reserve University in Cleveland, Ohio, says that the court is widely expected to side with the EPA, in which case the states would almost certainly appeal to the Supreme Court. Trump has promised to repeal the Clean Power Plan, and his administration is not expected to defend the regulations in court. But the president cannot reverse the regulations himself without providing a valid, non- political reason, Adler says, citing a 1.

Supreme Court ruling. Formulating such a reason could take Trump’s EPA a great deal of time, and it may not finish before the Supreme Court rules on the pending case. Either way, Adler says, the legal fight over the Clean Power Plan is likely to extend for years, and the plan is unlikely to survive in its current form.

Are Stuhrling Watches Junk? Here's our Review! A lot of people often wonder if Stuhrling Watches are junk. Admittedly, it’s not often that people mention their brand.

When you think watches you usually think Tag Heuer, Rolex and Casio. But really, who the hell can afford them? Sure some of them have a lot of interesting features but none of them are what you can consider, essential.

A watch at the end of the day, needs to tell the time accurately- everything else is irrelevant. Stuhrling watches are the very essence of simplicity. That’s not a knock on them. Simple is good. Simple just works. Stuhrling watches are also well made and easily accessible –whatever your budget there’s a stuhrling watch for you. The following are among the best Stuhrling watches for the money that you can buy at the moment. We will also discuss their positive and negative points so you can choose the best match for your needs.

Best Stuhrling Watches in 2. Overview of Stuhrling Watches. Stuhrling is an American company founded by Henry Fischer in New York in the year 1. They named the company in honor of prolific Swiss watchmaker Max Stuhrling. The brand gets overlooked the same way people overlook Japanese brands.

If it’s not from Switzerland, then it’s probably not that valuable. They manufacture the watches in China but you can’t really hold that against them. A lot of people equate china with piss poor quality. But I ask you, name one product that you can’t trace back to China?

Everything we use has at least one part that was manufactured there. Even Apple uses Chinese factories. People need to realize that the ? Easy, we review them for you. You will find the reviews of the most interesting watches in their line. Style. Style wise they really are an impressive piece of kit. Flashy without being gaudy.

These watches are made to stand out of the crowd. They have such a diverse series of collections that it’s guaranteed that you can find a watch to match you.

If you want simple, they have the Aviator collection. IF you want fancy, then you can get the Legacy Collection. There are also a lot of semi- skeleton designs, skeleton designs and other designs where the interior workings of the timepiece are clearly visible. Build Quality. Consider the materials they use for a Stuhrling watch. Only the highest quality materials have been used. For the bands, they use top grain genuine leather.

The body of the watches are made out of 3. L surgical- grade stainless steel. In Premier and limited edition timepieces they use exotic materials like genuine crocodile leather, ceramic cases and Swiss- made movements. Sounds like a quality watch to me. You can find the warranty card inside the packaging.

They do require that the watch be serviced by qualified professionals in Stuhrling original service centers. A third party watch repair shop may render your warranty null and void so you have that to watch out for. Based on the literature found in their website, they can complete service requests within six weeks (1.

Here Are Our Top 1. Stuhrling Watches Reviews!#1 Stuhrling Original Men’s 1. Classic Ascot Somerset Elite Swiss Quartz Watch with Mesh Bracelet.

Round Shape with hydraulically stamped knife- grip texture at inner dial and Arabic numeral and notch hour markers. L Surgical grade stainless steel) with Krysterna crystal dial window. The stainless steel body and band combo really stands out. The mesh band can looks great but you might have issues trying to find someone who can change the fit. The synthetic sapphire crystal also looks great – honestly it’s indistinguishable from authentic sapphire. It’s very well engineered. The slim construction lends itself very well to long sleeve clothing.

I’ve never had an issue with it getting stuck on a sleeve. The few weeks I have had it, I have never had to reset the time.

I’m pretty active and the watch was subjected to hard bumps and harsh vibration yet it has kept time without a hitch. Well built body –extremely sturdy. Very easy to clean glass. Not easily scratched.

Slim design (not too bulky)The clasp is pretty flimsy. There were times when it came loose. There were reported instances of the batteries being DOA. I personally haven’t experienced this. Arm hair can get caught in the metal band. Round Stainless Steel body with a black dial and luminous markers. Counterclockwise rotating bezel screw down crown with a magnified date window inset at the 3 o’clock position.

Krysterna crystal dial window. Japanese quartz movement with analog display. Stainless steel link cracelet with fold over clasp and safety. Water resistant up to 5. Suitable for short periods of recreational swimming but not diving or snorkeling. Similar to the Ascot somerset, the Regatta has a plain simple design. The black and silver simply looks clean and classy.

The date window is just the right size for the watch (some cases you’d need a microscope to see it) Japanese quartz movement looks smooth and goes without a hitch. The face is visible in all light conditions. I’m not a diver but they say it is water resistant up to 6. I’m going to have to take their word for it. The “do not take into the shower” in the manual is a tad bit confusing though. The packaging it came with looks really good. Inside you get additional links and microfiber cloth (for cleaning).

You also receive a registration card for your warranty (2 years)Water resistant. Unidirectional bezel.

Stainless steel looks great and is extremely durable. These are one of those things that looks like a thousand dollars- but is really worth a fraction of that. The simple brushed stainless body only drives the eye’s focus straight into the watch’s exposed inner workings. It’s simple yet eye catching at the same time. This watch is also self- winding. Which means, you don’t ever have to worry about batteries ever again. However, you have to wear the watch for 8 hours a day (it’s powered by your arm movements) or it will run slow.

It’s not really a bother. These watches are meant to be worn.

They’re not too expensive that you’ll worry about breaking them. If you do break them, they’re cheap so it’s no big deal anyway.

Shatter resistant glass. Water resistant up to 5. Self- winding movement. You need to wear it at least 8 hours a day to keep the time. Faux Leather strap fades easily.

Elegant stainless steel watch featuring skeleton dial with animated sun and moon display. Krystema crystal dial window. Automatic self- wind movement with analog display. Leather calfskin band with deployment clasp with push button closure. Water resistant - withstands splashes and rain but not immersion. This is one of those times where you either love it or hate it.

To be honest I did not like the design. But I love simple minimalist designs. However, if you love complex bold designs, this might be the watch for you. The watch is all large chunky metal featuring bold curves.

It looks like an old timey pocket watch bolted to a leather strap. I’m not exactly a fan of the design- but again, your mileage might vary. It also features a skeleton dial (see through) which I admit, looks pretty amazing. The sun and moon dial is a nice touch. As with the other high end stuhrlings, it features automatic self- wind movement- which means you don’t have any batteries to worry about. Automatic self- wind movement. Water resistant. Calfskin leather.

Stainless steel case. Not water proof. You need to wear it 8 hours to keep time accurate. Band is not standard width, not replaceable. Stainless steel round watch. Unidirectional ratcheting bezel and screw down crown. Swiss quartz movement and analog display.

Protective Krysterna Crystal dial window. Water- resistant to Blue dial featuring lumninous hands and date window. As usual at first glance this watch is impressive. The packaging looks premium. You’ll find everything you need in the box. The blue face have nice rich blue color. The weight is just right (not too heavy) and feels nice on your wrist.

The date window is a bit small for me but then again I have bad eyes. The band is made out of steel and can easily be adjusted.